时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
Emerging clinical evidence suggests that sertraline exposure may be associated with acquired multiple acyl-CoA dehydrogenase deficiency (MADD)-like metabolic abnormalities, but the underlying mechanism remains unclear. Differentiated C2C12 skeletal muscle cells were exposed to sertraline to evaluate acylcarnitine profiles, mitochondrial b…
对本项目的价值
参考价值：属「线粒体质量控制与氧化应激」方向；线粒体功能与氧化应激栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.8/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：舍曲林破坏 ETFDH 介导的线粒体脂肪酸氧化并促进长链酰基肉碱蓄积
- 英文标题：Sertraline disrupts ETFDH-mediated mitochondrial fatty acid oxidation and promotes long-chain acylcarnitine accumulation.
- 期刊与标识：Biological chemistry · PMID 42968638 · DOI 10.1515/hsz-2026-0226