时间标签：数据日期 2026-11-01 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31–2026/11/01 ｜ 情报发生日期 2026-11-01
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
Frailty is associated with adverse outcomes after metabolic and bariatric surgery (MBS).
方法
Existing bariatric frailty scores include MBSAQIP-derived tools, but reported discrimination is modest and prior accumulating-deficit indices used earlier or restricted cohorts.；We conducted a retrospective analysis using the MBSAQIP 2023-2024 cohort, including adults undergoing sleeve gastrectomy or Roux-en-Y gastric bypass as a primary or conversion MBS.；The data were randomly split into FI-derivation and validation cohorts (70%/30%, respectively).；The study identified 359,767 patients, of whom 252,043 were in the derivation cohort.
核心结论
Frailty is associated with adverse outcomes after metabolic and bariatric surgery (MBS).；Higher MBS-FI scores were progressively associated with adverse outcomes.；Although the MBS-FI demonstrated numerically higher discrimination for 30-day and in-hospital mortality, these differences were not statistically significant in the overall cohort (p = 0.33 and p = 0.49, respectively.
局限
（原文未给出可直接抽取的对应表述）
对本项目的价值
人群纵向证据，可用于假说生成与终点选择：功能结局（衰弱 / 肌少症）是临床转化最可及的终点，适合作为一期终点候选。 ｜ 价值分 1.6/5（★★☆☆☆）
全文来源
未取到全文 → 本卡为摘要级解读，未核验全文
原文题录
- 英文标题：Development and Internal Validation of a Metabolic and Bariatric Surgery Frailty Index (MBS-FI).
- 期刊与标识：Obesity surgery · PMID 42955611 · DOI 10.1007/s11695-026-08997-4
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。