时间标签：数据日期 2026-10-31 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/28–2026/10/31 ｜ 情报发生日期 2026-10-31
研究问题
The global population is aging at an accelerating pace, presenting a major challenge to public health and social systems worldwide and placing unprecedented strain on healthcare and long-term care infrastructures ().；Despite its conceptual promise, empirical research on IC trajectories, particularly studies adopting a multidimensional perspective, remains limited.；However, existing evidence has several limitations.
方法
All participants were from the SAGE-China cohort, a prospective cohort study conducted in six countries (China, Ghana, India, Mexico, Russia, and South Africa) ().；The Chinese SAGE cohort was carried out in eight provincial-level administrative regions (Jilin, Zhejiang, Shandong, Guangdong, Hubei, Shaanxi, Yunnan, and Shanghai).；Data for this dynamic cohort study were drawn from three waves of the WHO Study on Global AGEing and Adult Health (SAGE) China: Wave 1 (2007–2010), Wave 2 (2014–2015), and Wave 3 (2018–2019).；From an initial pool of 18,673 participants across the three waves, participants without available follow-up information, those younger than 50 years at baseline, and those with missing key variables were excluded.
核心结论
During follow-ups, the proportion of participants aged ≥70 years increased markedly from 19.44% wave 1(baseline) to 49.97% at wave 3.；We also observed significant change of marital status, with unmarried participants (never married, separated, divorced, or widowed) increasing from 12.61 to 21.69%.；Clean fuel usage increased from 50.15 to 67.18%. ‖ 结论：These findings highlight population groups and contextual factors that may warrant greater attention and provide evidence to inform population-level strategies for promoting healthy ageing within the broader healthy ageing framework.
局限
However, this interpretation should be viewed cautiously because age, period, and cohort effects are inherently intertwined in observational data.；The heterogeneity of IC progression may reflect differences in socioeconomic conditions, health status, and environmental contexts.；These findings may help identify population groups and contextual factors warranting greater attention in future healthy ageing strategies.
对本项目的价值
★☆☆☆☆ 脑老化是最大未满足需求，也是终点最难量化的领域；biomarker 与认知读数选择最敏感。
全文来源
PMC JATS 全文（正文 35,976 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Mapping the diverse trajectories of intrinsic capacity and their key drivers in China's aging population.
- 期刊与标识：Front Public Health · PMID 42959126 · DOI 10.3389/fpubh.2026.1923924
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
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