时间标签：数据日期 2026-11-01 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31–2026/11/01 ｜ 情报发生日期 2026-11-01
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
The objectives of the study were to: 1) compare dementia incidence in newly-diagnosed patients with HF or matched non-HF controls; and 2) examine risk factors for and outcomes after dementia diagnosis in HF patients.
方法
The objectives of the study were to: 1) compare dementia incidence in newly-diagnosed patients with HF or matched non-HF controls; and 2) examine risk factors for and outcomes after dementia diagnosis in HF patients.
核心结论
Incident dementia was associated with higher multivariable-adjusted hazards of all-cause mortality (HR: 2.44; 95% CI: 2.40-2.49) and all-cause hospitalization (HR: 1.63; 95% CI: 1.58-1.69) in outpatients with HF (all P < 0.001).；Rates of outpatient physician visits with primary care, internal medicine, cardiologists (post/pre-rate ratio range 1.08-1.19), and geriatricians (post/prerate ratio 10.70; all P < 0.001) were higher after (versus before) dementia onset.；Incident HF was associated with higher risk of incident dementia.；Dementia onset was associated with higher rates of outpatient physician visits and increased risk of adverse outcomes.
局限
（原文未给出可直接抽取的对应表述）
对本项目的价值
临床前机制证据，需评估物种外推与剂量可行性：血管老化是全身衰老的先行指标，可与其他时钟做交叉验证。 ｜ 价值分 1.0/5（★☆☆☆☆）
全文来源
未取到全文 → 本卡为摘要级解读，未核验全文
原文题录
- 英文标题：Incidence of Dementia and Subsequent Outcomes in Patients With Heart Failure.
- 期刊与标识：JACC. Advances · PMID 42954690 · DOI 10.1016/j.jacadv.2026.103248
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。