时间标签：数据日期 2026-10-29 · 生成时间 2026-10-31 05:30（Asia/Shanghai）｜ 档位：观察哨26 ｜ 窗口 T-2 ｜ 上游评级 C
这项研究想回答什么
社区痴呆人群中，数字化防跌倒方案是否可行？
方法与数据
两臂平行、非盲可行性 RCT，干预组 30 例、对照组 30 例，干预为每天 30 分钟、每周 3 次、共 6 周的平板端 KOKU-LITE；两组均随访至 6 周。
核心结论
以下所有数字均可在官方 abstract 原文（见第 7 节）中逐字核对；上游未给出的定量一律写「未给出」，不估算、不换算。
- 一句话贡献：60 名 ≥55 岁社区痴呆患者随机入组，接触者中 87%（60/69）同意参加、6 周保留率 90%（54/60），干预期未报告严重不良事件（含伤害性跌倒）。
局限与未核验项
可行性研究、样本仅 60 例、随访 6 周，摘要明示未 powered 检验有效性，且非盲设计、无客观跌倒率结局。
补全文时优先核：依从性数据（每天 30 分钟、每周 3 次的实际完成率）、跌倒事件的记录方式、对照组的活动内容。
⚠️ 本页为摘要级解读：未取得 PDF 全文，上述所有结论均未核至 Results/Methods；效应量、样本量、统计方法与多重比较校正在多数条目中仍未知。
对本领域的价值
痴呆照护与跌倒预防，与衰老生物学机制关联薄弱，属长尾命中；价值在真实世界可执行性，非机制深读对象。
编辑研判
与衰老生物学机制关联薄弱，价值在真实世界可执行性：60 名 ≥55 岁社区痴呆患者随机入组，接触者 87%（60/69）同意、6 周保留率 90%（54/60），干预期无严重不良事件（含伤害性跌倒）。对做老年干预可行性设计的人，这些招募与保留率是可用参数。但它明确定位为可行性研究（未 powered 检验有效性、非盲、无客观跌倒率结局），不能当作有效性证据引用。
官方摘要原文（逐字，供回溯）
展开 api.biorxiv.org / api.medrxiv.org 返回的 abstract 原文
Background: Falls are common and costly among people living with Dementia (PLwD). Keep on Keep up (KOKU) is a UK National Health Service (NHS) approved tablet-based, digital gamified programme with strength and balance exercises and health literacy games, designed with and for older people at risk of falls. KOKU-LITE is a dementia-friendly accessible version of KOKU that has been co-developed with PLwD to meet their needs. This study aimed to assess the feasibility, usability and acceptability of KOKU-LITE among community dwelling PLwD in terms of recruitment, retention and user experience of the intervention. Methods: This is a two-arm, parallel, non-blinded, feasibility randomised controlled trial. Sixty people aged 55 years and over living with dementia were recruited across Greater Manchester, UK, and randomised to either intervention group (KOKU-LITE plus dementia falls prevention leaflet) or control group (dementia falls prevention leaflet). Intervention participants were asked to use KOKU-LITE for 30 minutes a day, three times per week for six weeks. Both groups were followed up to six weeks. Primary outcomes were feasibility, usability and acceptability assessed using recruitment and retention rates, and user experience measured by user experience questionnaire. Trial registration: https://clinicaltrials.gov/study/NCT06149702. Findings: Sixty participants (30 intervention, 30 control) were recruited and followed up between March 2024 to September 2025. Among those approached, 87% (60/69) consented to participate, 90% (54/60) were retained at six weeks follow up. Overall, the user experience findings indicated strong acceptability and generally positive perceived usability and engagement. No serious adverse events, including injurious falls, were reported during the intervention period. Interpretation: KOKU-LITE was feasible to deliver and acceptable to PLwD in a home-based community setting. Although the study was not powered to assess effectiveness, the findings support progression to a definitive trial, with refinement of outcome selection, intervention-use monitoring and follow-up duration. Funding: National Institute for Health and Care Research (NIHR) and Alzheimers Society (Award number: NIHR200174).
本文为预印本，未经同行评审，结论可能在正式发表时变更。生成任务 12819187（预印本全文级解读）· 上游 12784209（预印本速递）。
C 级证据分级：C 级（预印本，未经同行评审；本页为摘要级，未核至全文）
本文为预印本，未经同行评审；且本页为「摘要级」——未取得 PDF 全文（源站封锁），全部结论只依据官方 API 摘要原文。效应量、样本量、统计方法与多重比较校正在多数条目中仍未知，摘要未给出之处一律写「未给出」/「待补全文」，未做任何数值推算补全。
关于本文的文献来源：本站依据元层《预印本全文级解读_2026-10-31》（上游《预印本速递_2026-10-31》）撰写，附官方 abstract 原文供逐字回溯。