时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
研究问题
The potential consequences depend on the genomic position of the repeat within an exon, including whether it occurs in a coding or untranslated exon.；However, whether exonic SSRs are preferentially distributed among genes with specific biological functions remains poorly understood, particularly in avian genomes.Diving ducks (tribe Aythyini) provide an attractive system for investigating these questions.；The order of the four themes was used for presentation and did not represent a formal ranking of biological importance or statistical significance.2.8.Assessment of Gene‐Architecture BiasTo evaluate whether gene architecture could influence the occurrence or detection of exonic SSRs, we compared summed annotated exon length and gene genomic span between the shared exonic SSR‐containing genes and independent background genes in each species.
方法
Ecology and Evolution published by British Ecological Society and John Wiley & Sons Ltd.This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.ABSTRACTSimple sequence repeats (SSRs) are ubiquitous components of eukaryotic genomes that contribute to genome evolution, genetic variation, and gene regulation.；To address this knowledge gap, we performed a comparative analysis of chromosome‐level genome assemblies from three diving duck species ( Aythya ferina , Aythya marila , and Netta rufina ) to investigate genome‐wide SSR patterns and the cross‐species sharing and functional characteristics of exonic SSR‐containing genes.；Comparative analyses of genome‐wide SSRs revealed pronounced interspecific variation in SSR abundance and repeat composition, whereas exonic SSR abundance showed more similar values after normalization by total annotated exon sequence length.
核心结论
Collectively, our results reveal distinct patterns for genome‐wide and exonic SSRs distribution among the three diving duck species and identify shared functional associations of genes containing exonic SSRs.；These findings provide a comparative genomic framework for future investigations of exonic SSRs in waterfowl and other non‐model vertebrates.Keywords: avian genomics, comparative genomics, diving ducks, exonic SSRs, gene ontology, KEGG, simple sequence repeatsComparative analysis of chromosome‐level genomes from three diving duck species revealed pronounced interspecific variation in genome‐wide SSR abundance and repeat composition, while identifying 4336 exonic SSR‐containing genes shared among all three species.；Increasing evidence, however, indicates that microsatellites are not merely neutral genetic markers but also represent important components of genome architecture that may influence genome evolution, gene regulation, and phenotypic diversification (Li et al. 2004; Gemayel et al. 2010).
局限
These functional associations should be interpreted cautiously because they may be influenced by cross‐species annotation limitations and gene‐architecture differences.；Functional enrichment analyses of these shared genes highlighted four broad functional themes related to transcription and epigenetic regulation, protein homeostasis, development, and stress response, although these associations should be interpreted cautiously in light of annotation limitations and potential gene‐architecture bias.；Increasing evidence, however, indicates that microsatellites are not merely neutral genetic markers but also represent important components of genome architecture that may influence genome evolution, gene regulation, and phenotypic diversification (Li et al. 2004; Gemayel et al. 2010).
对本项目的价值
中高价值：属「营养感知—自噬—蛋白稳态轴」方向；mTOR / 自噬 / 蛋白质稳态栏目可用作本项目文献库与综述素材。 ｜ 价值分 3.0/5（★★★☆☆）
全文来源
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原文题录
- 中文题名：三种潜水鸭外显子 SSR 基因的比较分析揭示共同功能主题
- 英文标题：Comparative Analysis of Exonic SSR-Containing Genes in Three Diving Duck Species Reveals Shared Functional Themes.
- 期刊与标识：Ecology and evolution · PMID 42969019 · DOI 10.1002/ece3.74632 · PMC PMC13724249