研究进展

败血梭菌菌血症并发自发性产气肌炎并揭示疑似盲肠癌

来源:Cureus · PMID 42979350 · DOI 10.7759/cureus.117442 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-05 期 · 全文级(file_id dAlZBwueyWSz,实际下载核验 1,395,640 B) · 全文已获取并通过三重归属校验

时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05

研究问题

In our patient, the right leg swelling and subsequent hip pain led to cross-sectional imaging, which showed both the gas-forming infection and the caecal lesion.Whether to pursue histological confirmation was a separate consideration.

方法

We describe a case in which C. septicum bacteraemia, complicated by gas-forming myositis in the hip and pelvis, led to the discovery of a suspected caecal malignancy in a frail older woman.Case presentationA 79-year-old woman with a Clinical Frailty Scale score of 6 [8] was admitted with a several-day history of vomiting, diarrhoea, fever, rigors, breathlessness, and reduced mobility.;She had a background of transitional cell carcinoma of the renal pelvis (G2pTa), treated previously with nephroureterectomy, type 2 diabetes mellitus, a right lacunar infarct, and a silent myocardial infarction complicated by severe left ventricular dysfunction and cardiogenic shock (ejection fraction 11%).;Clinicians who isolate this organism from blood cultures should maintain a low threshold for cross-sectional imaging of both the musculoskeletal system and the colon, even in frail patients in whom curative treatment may ultimately not be feasible, so that the diagnosis, prognosis, and goals of care can be established as early as possible.

核心结论

(原文未给出可直接抽取的对应表述)

局限

However, serial inflammatory markers showed a sustained response to treatment.;Relying on imaging alone carries real limitations.;However, her frailty score, severely impaired cardiac function, and limited physiological reserve meant that she would not have been a candidate for resection, and a tissue diagnosis would not have altered her management [9].

对本项目的价值

中等价值:属「衰弱 / 肌少症功能结局」方向;肌肉骨骼 / 衰弱 / 肌少症栏目可用作本项目文献库与综述素材。 | 价值分 2.6/5(★★★☆☆)

全文来源

PubMed PMC JATS(正文 12,242 字符,题名指纹 0.92,已过 PubMed PMCID 官方关联 + 题名指纹 + 正文长度归属校验)

原文题录

  • 中文题名:败血梭菌菌血症并发自发性产气肌炎并揭示疑似盲肠癌
  • 英文标题:Clostridium septicum Bacteraemia Complicated by Spontaneous Gas-Forming Myositis Revealing a Suspected Caecal Cancer.
  • 期刊与标识:Cureus · PMID 42979350 · DOI 10.7759/cureus.117442 · PMC PMC13730541

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

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