时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
Triple-negative breast cancer (TNBC) is refractory, which could be likely ascribed to cancer stem cells (CSCs) harbored in TNBC. Therefore, to develop a novel therapeutic strategy for TNBC by targeting CSCs, we established and characterized 4T1-derived CSC-like cells. First, cell clones were obtained from a single mouse TNBC 4T1 cell util…
对本项目的价值
参考价值：属「干细胞 / 部分重编程与再生」方向；干细胞 / 再生 / 重编程栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.8/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：来源于单个小鼠三阴性乳腺癌 4T1 细胞的癌干样细胞表征：Akt-mTOR 通路参与增殖与成球
- 英文标题：Characterization of cancer stem-like cells derived from a single 4T1 murine triple-negative breast cancer cell: Involvement of Akt‒mTOR pathway in the proliferation and sphere formation.
- 期刊与标识：Archives of biochemistry and biophysics · PMID 42977047 · DOI 10.1016/j.abb.2026.111050